Prevention is better than cure, so if you travel somewhere, consider leaving your luggage far away from any upholstered surfaces until you have a chance to inspect it and clean your clothing. If you're planning on buying second-hand furniture, ensure you thoroughly examine it before bringing it inside.
As well as visible bugs and eggs, a strong odour and blood stains can both be a sign of bedbugs. Regularly cleaning your mattress, letting it air once a week and washing your bedding at least once a week will help deter pests.
If you find yourself with a bedbug problem, you will likely need professional help, since it's extremely hard to eradicate an established infestation. Wash infested bedding at a minimum of 60°C (140°F) for at least 90 minutes and, if possible, place items in the tumble dryer for a minimum of 30 minutes. You could also vacuum or steam the infested area, too, but if the problem persists, call in the experts.